ABSTRACT
One of today's environmental crisis that industrial technology it produces. Lead is one of the most important environmental contaminants that prolonged contact with the production of free radicals. Study results show that air pollution is increases mortality due to cardiovascular disease. To study the effects of consumption turmeric extracts on prooxidant- antioxidant balance of rats' spleen and heart tissues exposed to lead acetate. Thirty-six male rats randomly were classified into four groups as: 1] Basic, 2] Sham [turmeric solvent], 3] Lead, 4] turmeric extract+lead, [each group includes 9 rats]. Turmeric supplements were injected three times per week and total of 8 weeks to 30 mg/kg body weight. Injection protocol lead and turmeric extract or solvent [ethyl first] three sessions a week and will run for 8 weeks, all injections were in peritoneally. After separation of spleen and heart tissues and homogenization, showed; injection of lead increases the index of lipid peroxidation in spleen and heart tissues. Also turmeric supplementation inhibits oxidative effects on the spleen and heart. Based on this research findings using a healthy style, and herbal supplements is effective in reducing the harmful effects anti-oxidation pollutants
ABSTRACT
Septic arthritis of the hip in children has multiple sequelae and may result in severe disability. Significant morbidity can be prevented by early recognition and treatment. The authors reviewed 13 children with 14 hips with sequelae of septic arthritis of the hip. All of children had history of hip septic arthritis before age of 4 years. Six were male subjects, and 7 were female subjects. We evaluated the history, clinical findings and radiographs of all children who had been treated at the Imam Khomeini hospital between 1986 and 2001 for septic arthritis of the hip. Final results of operations in patients include range of motion, presence or absence pain, joint stability, limb-length discrepancy were assessed. Three hips had mild pain in usual daily activities and one patient with cerebral palsy experienced hip instability. Most of patients [80%] had flexion contracture about 10-15 degrees .Final results showed average limb length discrepancy was about 2.8 cm. Septic arthritis of the hip in children may result in a spectrum of residual problems and the significant complications can be averted by early detection and treatment. Treatment in younger age cause better outcome.
ABSTRACT
Anterior knee pain is one of the most common complaints of patients in orthopedic clinics. The first step in the treatment of this problem is conservative treatment which includes administration of anti-inflammatory drugs, exercise and changes in life style. Many patients respond well to these measures in about six months, but a small number of patients may not respond to the conservative treatment; therefore, surgical procedures such as Maquet osteotomy or lateral retinacular release may be needed in these cases. The aim of this study was to determine the efficacy of intraosseous drilling and decompression of patella in the treatment of chronic anterior knee pain. This study was performed as a case series on ten patients with chronic anterior knee pain attending the Orthopedic Clinic of Imam Khomeini Hospital, in Tehran, Iran in 2009-2010. Eight of the patients were male and the rest were female. The patients met the inclusion criteria and were followed up for at least 12 months after the surgery. The mean age of the patients was 27.8 +/- 4.66 yr and their mean BMI was 22.5 +/- 1.71 kg/m2. The mean pain severity before the interventions was 8.2 +/- 0.78 based on VAS but it decreased to 2.5 +/- 1.26 post-surgically. An average reduction of 5.7 scores were noticed in pain severity depicting a significant reduction of pain [P<0.0001]. It may be concluded that intraosseous drilling and decompression of patella is a safe and effective method in the treatment of chronic anterior knee pain not responding to conservative treatment
Subject(s)
Humans , Male , Female , Decompression, Surgical , PatellaABSTRACT
Environmental pollution is of major concern today and lead is considered to be one of the most important environmental pollutants. Long-term contact with lead causes harmful effects to humans. This study seeks to determine the effects of Curcuma longa [turmeric extract] consumption and exercise training on glutathione peroxidase and protein carbonyl in kidney and spleen tissues from rats exposed to lead. We randomly classified 60 male rats into the following six groups of 10 rats per group: 1] control; 2] sham [turmeric extract solvent]; 3] lead; 4] training + lead; 5] turmeric extract + lead; and 6] training + lead + turmeric extract. The training program for groups 3 and 6 consisted of running on a level treadmill for 40 sessions [eight weeks at five sessions per week] at a speed of 22 to 15 m/min for 26 to 64 minutes. Turmeric extract [30 mg/kg] was injected three times per week for eight weeks. Amounts of glutathione peroxidase and protein carbonyl were measured by ELISA. The amount of protein carbonyl in the kidney and spleen tissues of the lead group increased compared to the sham, training, combined and extract groups. Rats in the combined, extract and practice groups [F=4.787; P=0.002] had lower levels of protein carbonyl in their kidney and spleen tissues compared to the sham group [F=6.970, P=0.000]. Glutathione peroxidase levels in the kidney and spleen tissues were less in the lead group compared to the sham group. However these levels in the training, extract, and combined groups increased compared with the sham group [respectively, in kidney and spleen P=0.051, F=2.466 and P=0/086, F=2.11]. Intake of turmeric extract and exercise alone did not cause complete inhibition of the oxidative effects in kidney and spleen tissues. However, exercise and consumption of turmeric extract can be effective in reducing the harmful effects of lead